Publications

Peer-reviewed articles, listed chronologically (most recent first). Names of co-corresponding authors are marked with *; co-first authors with †. My name is highlighted.

2025

1. Kim SC^†, Lee SA^†, Kim MJ, Shin YK, Kim HS, Jeong SY, Ku JL, Park JW. Pressurized intraperitoneal aerosol chemotherapy enhances cisplatin efficacy in colorectal cancer organoids. Sci Rep. 2025 Dec 19;15(1):44165.
2. Kim CY, Kim SC, Shin R, Kim MJ, Jeong SY, Park JW, Ku JL. Integrative multi-omics of matched primary and liver metastatic colorectal cancer organoids identifies putative molecular targets. Transl Oncol. 2025 Nov 4;63:102592.
3. Kim SC^†, Kim GH^†, Park JH, Lee KH, Koh J, Kim TY, Lee DW, Kim YJ, Kim S, Park SY, Min A, Shin YK, Im SA^*, Ku JL^*. Establishment and characterization of 24 breast cancer cell lines and 3 breast cancer organoids reveals molecular heterogeneity and drug response variability in malignant pleural effusion-derived models. Breast Cancer Res. 2025 May 1;27(1):66.
4. Maeng JE, Kim JH, Kim SC, Yun WG, Kwon W, Han Y, Oh DY, Lee SH, Jang JY^*, Ku JL^*. Comprehensive molecular analysis of 26 newly established human pancreatic ductal adenocarcinoma cell lines reveals two clusters with variating drug sensitivities. Cancer Cell Int. 2025 Feb 19;25(1):53.
5. Kim MJ, Song MH, Ji YS, Park JW, Shin YK, Kim SC, Kim G, Cho B, Park H, Ku JL^*, Jeong SY^*. Cell free supernatants of Bifidobacterium adolescentis and Bifidobacterium longum suppress the tumor growth in colorectal cancer organoid model. Sci Rep. 2025 Jan 6;15(1):935.

2024

1. Kim SC^†, Kim MJ^†, Park JW, Shin YK, Jeong SY^*, Kim S^*, Ku JL^*. Effects of simulated microgravity on colorectal cancer organoids growth and drug response. Sci Rep. 2024 Oct 26;14(1):25526.
2. Cho YE^†, Kim SC^†, Kim HJ, Han I, Ku JL^*. Establishment and characterization of 18 Sarcoma Cell Lines: Unraveling the Molecular Mechanisms of Doxorubicin Resistance in Sarcoma Cell Lines. J Transl Med. 2024 Oct 2;22(1):889.
3. Kim SC^†, Seo HY^†, Lee JO, Maeng JE, Shin YK, Lee SH, Jang JY^*, Ku JL^*. Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer. Cell Oncol (Dordr). 2024 Oct;47(5):1627–1647.
4. Wang SS, Hall ML, Lee E, Kim SC, Ramesh N, Lee SH, Jang JY, Bold RJ, Ku JL, Hwang CI^*. Whole-genome bisulfite sequencing identifies stage- and subtype-specific DNA methylation signatures in pancreatic cancer. iScience. 2024 Mar 4;27(4):109414.

2023

1. Kim SC, Cho YE, Shin YK, Yu HJ, Chowdhury T, Kim S, Yi KS, Choi CH, Cha SH^*, Park CK^*, Ku JL^*. Patient-derived glioblastoma cell lines with conserved genome profiles of the original tissue. Sci Data. 2023 Jul 12;10(1):448.

2022

1. Jeong N^†, Kim SC^†, Park JW, Park SG, Nam KH, Lee JO, Shin YK, Bae JM, Jeong SY^*, Kim MJ^*, Ku JL^*. Multifocal organoids reveal clonal associations between synchronous intestinal tumors with pervasive heterogeneous drug responses. NPJ Genom Med. 2022 Jul 19;7(1):42.
2. Song MH, Park JW, Kim MJ, Shin YK, Kim SC, Jeong SY^*, Ku JL^*. Colon cancer organoids using monoclonal organoids established in four different lesions of one cancer patient reveal tumor heterogeneity and different real-time responsiveness to anti-cancer drugs. Biomed Pharmacother. 2022 Aug;152:113260.
3. Seo HY^†, Kim SC^†, Roh WL, Shin YK, Kim S, Kim DW, Kim TM^*, Ku JL^*. Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types. Sci Rep. 2022 Apr 15;12(1):6345.
4. Lee JH, Kim H, Lee SH, Ku JL, Chun JW, Seo HY, Kim SC, Paik WH, Ryu JK, Lee SK, Lowy AM, Kim YT^*. Establishment of Patient-Derived Pancreatic Cancer Organoids from Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsies. Gut Liver. 2022 Jul 15;16(4):625–636.
5. Kim SC, Park JW, Seo HY, Kim M, Park JH, Kim GH, Lee JO, Shin YK, Bae JM, Koo BK, Jeong SY^*, Ku JL^*. Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses. Adv Sci (Weinh). 2022 Feb;9(5):e2103360.

2020

1. Seo J, Lee CR, Paeng JC, Kwon HW, Lee D, Kim SC, Han J, Ku JL, Chae JH, Lim BC, Choi M^*. Biallelic mutations in ABCB1 display recurrent reversible encephalopathy. Ann Clin Transl Neurol. 2020 Aug;7(8):1443–1449.
2. Kim SC^†, Kim HS^†, Kim JH, Jeong N, Shin YK, Kim MJ, Park JW, Jeong SY^*, Ku JL^*. Establishment and characterization of 18 human colorectal cancer cell lines. Sci Rep. 2020 Apr 22;10(1):6801.

* Corresponding author(s). † Equal contribution.